Parkinson s Disease Is A Chronic Neurodegenerative Disorder

Parkinson’s disease is a chronic neurodegenerative disorder characterized by degeneration and cell loss of the substantia nigra, which causes disturbances of voluntary motor control [5]. It impairs ones ability to produce movements and is commonly associated with difficulties of daily living. Parkinson’s disease (PD) affects approximately 1.5% to 2.0% of the population over the age of sixty years old [2] and â€Å"†¦ it is estimated that 6 million individuals worldwide are currently living with PD,† [7] (pg323). Parkinson’s sufferers often experience physical distress and an altered quality of life. Pathophysiology, Risk Factors and Diagnostic Techniques A popular joke among college science majors is â€Å"you make my dopamine levels go all silly,† in reference to the physiological function of dopamine linked to hormone secretion and emotional behavior. However, dopamine plays an important functional role in movement the generation of movement [4]. A deficiency of dopamine levels in the brain leads to many life-altering side affects experienced by patients suffering from Parkinson’s disease. Parkinson’s disease is identified as a chronic progressive neurodegenerative disorder of the brain affecting the nigrostriatal dopaminergic system [1]. Among the basal ganglia network, clusters of nerve cells known as substantia nigra and their nuclei, synthesize dopamine by mesencephalic neurons [2]. It is the slow disintegration of substantia nigra that lead to Parkinson’s disease affectingShow MoreRelatedBiological Hazards And Physical Hazards1051 Words   |à ‚  5 Pagesresponse and related behavioral pathways through neural networks and interconnected neurohormonal and immune patterns. The capacity of human beings to learn about, imagine, remember, and anticipate stressful situations and their warning signs can create chronic states of vigilant arousal in the body. Besides, there are multiple individual differences that make some people more vulnerable to stress, where the identical stimuli cause exaggerated stress responses (ES-2014). Gene-environment interactions inRead MoreImplement And Monitor Nursing Care For Clients With Chronic Health Problems1427 Words   |  6 PagesClients with chronic health problems INTRODUCTION: Parkinson disease mainly defined as the death of certain brain cells. These brain cells mainly control the body parts movement and the coordination. The disease mainly decrease the mobility which leads difficulty in walking (Medline Plus, 2016). Currently, Parkinson has no known cause which mainly effect people to develop this disease. Many theories tells that there are several factors that are responsible to cause Parkinson diseaseRead MoreThe Disease Of Parkinson s Disease1648 Words   |  7 PagesParkinson’s disease has been cataloged as one of the most serious and slowly progressive neurodegenerative disease that affects a wide array of motor and non-motor aspects that impact the function of a person. Afflicting over four million Americans and the second most common neurological disorder after Alzheimer’s disease, Parkinson’s continues to take its toll on the neurological health of many(Constantinescu et al, 2007 ). James Parkinson, a British physician first coined this disorder as â€Å"shakyRead MoreNot Only Is It Detrimental To The Social Development Of1604 Words   |  7 Pagesthat, â€Å"Many of these lifestyle changes have been shown to lower the risk of other diseases, like heart disease and diabetes, which have been linked to Alzheimer s† (Alzheimer s Association Organization). 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He was admitted into Sichuan University to study mechanical engineering; however, his tremble hands impeded him from sketching or writing, stultified his previous endeavors and evaporated his dreams. My father’s suffering is not an isolated case: millions of patients are plagued by these diseases. TheRead MoreParkinson’S Disease. Abstract. Parkinson’S Disease Is A2430 Words   |  10 PagesParkinson’s Disease Abstract Parkinson’s Disease is a very common disorder these days. Over 10 million people live daily with Parkinson worldwide. Parkinson’s Disease was named after an English surgeon James Parkinson who wrote a detailed description essay called Shaking Palsy in 1817. The average age for Parkinson’s Disease is between 45 to 70 years old but you can also have juvenile or young onset as well. Most common symptoms of Parkinson are tremors, bradykinesia or akinesia, or rigidity orRead MoreEssay on Parkinson’s Disease1305 Words   |  6 PagesParkinson’s Disease (PD) is a chronic neurological disease that effects about 329 per 100,000 people in the US. The average onset of this disease usually is for people over the age of 50, with the baby boomers getting older there may be an increase in this disease, as much as 9 million people worldwide. (Pawha 2010) Etiology The disease happens when the cells in the brain are damaged or stop-producing Dopamine, which helps with muscle movement, thus leaves those patients unable to control theirRead MoreI Will Choose Gene Therapy1799 Words   |  8 PagesI will choose gene therapy for this assignment. According to Genetics Home reference (2015), â€Å"gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient’s cells instead of using drugs or surgery.† Gene therapy made many medical accomplishments in less than two decades (American Society of Gene Cell Therapy, 2015). According to American Society of Gene Cell Therapy